Status:

COMPLETED

Organochlorine Concentration in Adipose Tissue and Pancreatic Adenocarcinoma

Lead Sponsor:

CHU de Reims

Conditions:

Carcinoma

Pancreatic Ductal

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Pancreatic adenocarcinoma represents more than 90% of pancreatic neoplasms. Around 14000 new cases of pancreatic adenocarcinoma are being diagnosed each year in France and about 8.6% in Grand Est regi...

Detailed Description

Unicentric prospective case control study comparing organochlorine levels including patients diagnosed with a pancreatic adenocarcinoma undergoing a surgery allowing to collect an adipose tissue sampl...

Eligibility Criteria

Inclusion

  • inclusion criteria :
  • Cases :
  • patients diagnosed with a pancreatic adenocarcinoma, all stages allowed
  • undergoing a surgery allowing to take a 10 grams adipose tissue sample
  • Controls :
  • patients without a pancreatic neoplasm on a 6 months old CT scan before inclusion
  • undergoing a surgery allowing to take a 10 grams adipose tissue sample
  • exclusion criteria :
  • Cases :
  • patients diagnosed with a pancreatic adenocarcinoma developed on IPMN or cystadenoma
  • patient with a known genetic predisposition increasing pancreatic adenocarcinoma risk
  • histopathology proof of a mixed neuroendocrine neoplasm
  • no surgery allowing to take a 10 grams adipose tissue sample
  • Controls :
  • patients with a pancreatic neoplasm on a 6 months old CT scan before inclusion
  • no surgery allowing to take a 10 grams adipose tissue sample

Exclusion

    Key Trial Info

    Start Date :

    June 12 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    May 15 2023

    Estimated Enrollment :

    56 Patients enrolled

    Trial Details

    Trial ID

    NCT04429490

    Start Date

    June 12 2020

    End Date

    May 15 2023

    Last Update

    October 10 2024

    Active Locations (1)

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    1

    Damien JOLLY

    Reims, France