Status:
NOT_YET_RECRUITING
Heterozygous Individuals for AGXT and Kidney Stones
Lead Sponsor:
University of Alabama at Birmingham
Conditions:
Kidney Stone
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study seeks to examine the effects of a heterozygous mutation of the AGXT gene in a stone forming population on endogenous oxalate production. Participants will consume a controlled low-oxalate d...
Eligibility Criteria
Inclusion
- at least 18 years of age
- history of calcium oxalate stones
- heterozygous mutation of the AGXT gene, as evidenced by results from the Invitae Nephrolithiasis Panel
- willingness to comply with a controlled diet for five days
Exclusion
- pregnant individuals
- individuals who are currently breast feeding
Key Trial Info
Start Date :
July 1 2026
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2032
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT04430426
Start Date
July 1 2026
End Date
August 1 2032
Last Update
July 4 2025
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