Status:
COMPLETED
Emotion-Diet Interactions in Pregnancy
Lead Sponsor:
University of California, Irvine
Collaborating Sponsors:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Conditions:
Pregnancy Related
Stress, Psychological
Eligibility:
FEMALE
18-40 years
Phase:
NA
Brief Summary
This study will investigate how maternal emotional state following a controlled stress exposure in pregnancy influences blood glucose and insulin levels after eating a standardized meal, and whether t...
Detailed Description
Maternal glucose-insulin homeostasis in pregnancy represents one of the most important physiological processes for maternal and child health outcomes. Although maternal diet is a key regulator of this...
Eligibility Criteria
Inclusion
- English and/or Spanish speaking
- 18-22 week's gestation
- Pre-pregnancy BMI 25.0-39.9 kg/m2
- Singleton, intrauterine pregnancy
- Non-smoker
- Non-diabetic and normal result on a random peripheral blood glucose test at the screening visit (\<200 mg/dl)
Exclusion
- Non-fluency in English or Spanish
- BMI \<25.0 or ≥40.0 kg/m2
- \>22 week's gestation
- multiple pregnancy
- current smoker
- present/prior obstetric conditions (preeclampsia, infections, placental abnormalities, uterine anomalies, congenital malformations, fetal chromosomal abnormalities)
- presence of any conditions that may dysregulate neuroendocrine, metabolic or cardiovascular function, such as diabetes, hepatic, renal, or autoimmune disorders
- current psychiatric disorders or undergoing treatment/taking psychiatric medications
- use of systemic/frequent corticosteroids or thyroid, lipid-lowering or anti-diabetic medications
- gestational diabetes mellitus or raised glucose result detected on the screening visit
- unwilling to eat the standard breakfast meal at each laboratory visit
Key Trial Info
Start Date :
May 11 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2024
Estimated Enrollment :
113 Patients enrolled
Trial Details
Trial ID
NCT04430439
Start Date
May 11 2021
End Date
February 28 2024
Last Update
August 22 2025
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
University of California, Irvine
Irvine, California, United States, 92617
2
UCI Medical Center, University of California, Irvine
Orange, California, United States, 92868