Status:

COMPLETED

Use of Tranexamic Acid in Liposculpture

Lead Sponsor:

Total Definer Research Group

Conditions:

Blood Loss, Surgical

Eligibility:

All Genders

20-45 years

Phase:

PHASE2

PHASE3

Brief Summary

Blood loss during a surgical procedure is inevitable, its reduction is a key factor for surgical success. Also, to avoid progress to severe complications like hemodynamic decompensation, cardiac arres...

Detailed Description

In 3 plastic surgery centers, the investigators randomized patients in a double-blind, randomized, controlled trial comparing the clinical outcomes of different administration routes of TXA, intraveno...

Eligibility Criteria

Inclusion

  • Patients that underwent liposculpture as unique procedure, surgical time between 2 and 5 hours, age between 20 and 45 years old and BMI between 20 and 30 m2/kg.

Exclusion

  • Patients that were operated of liposculpture and any additional procedure (Mammoplasty, tummy tuck, etc.), patients with history of thromboembolic disease or in Treatment with aspirin within 14 days before surgery or anticoagulants within 5 days prior to surgery, patients with history of epilepsy, patients with allergy to tranexamic acid, comorbidity grade III or IV according to ASA (American society of Anesthesiologists) and patients with prothrombin time (PT) and/or activated partial thromboplastin time (aPTT) \>1.5 times the baseline.

Key Trial Info

Start Date :

January 17 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 22 2020

Estimated Enrollment :

141 Patients enrolled

Trial Details

Trial ID

NCT04430777

Start Date

January 17 2019

End Date

February 22 2020

Last Update

June 12 2020

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Dhara clinic

Bogotá, Colombia

2

Innovare hospital

Jalisco, Mexico

3

Centro Medico de las Americas clinic

Mérida, Mexico