Status:

RECRUITING

Time and Virtual Reality in Schizophrenia and Bipolar Disorder

Lead Sponsor:

Institut National de la Santé Et de la Recherche Médicale, France

Conditions:

Schizophrenia

Bipolar Disorder

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

Patients with bipolar disorders report an acceleration or slowing of time flow, and patients with schizophrenic spectrum disorders a time fragmentation. These disorders would be linked to disorders of...

Eligibility Criteria

Inclusion

  • \- Participant, male or female, between 18 and 60 years old
  • Subject affiliated to a social health insurance scheme (beneficiary or entitled person)
  • Subject who has dated and signed an informed consent form
  • For a woman of childbearing age, negative pregnancy test and effective contraception throughout the study
  • A patient under guardianship, whose guardian has dated and signed a consent, as well as the patient if able.
  • A patient under guardianship, whose consent has been obtained, if necessary, by the guardian or with the assistance of the guardian, prior to the commencement of any trial-related procedures.
  • Patients only:
  • Patients with psychotic disorders (schizophrenia-like): Patients with diagnostic criteria for schizophrenia as defined by the DSM V (American Psychiatric Association, 2015).
  • Patients with Bipolar Disorder: A patient with diagnostic criteria for bipolar disorder as defined by the DSM V (American Psychiatric Association, 2015).

Exclusion

  • Substance Use Disorders (as defined by DSM-V)
  • Intake of benzodiazepines (in the period before inclusion, for a duration equivalent to 5 half-lives of the product), cannabis (in the 2 months before inclusion) or hallucinogenic substances (in the period before inclusion, for a duration equivalent to 5 half-lives of the product).
  • A neurological pathology or sequelae
  • Attention Deficit Hyperactivity Disorder (ADHD)
  • Borderline personality disorder
  • Disabling sensory impairment, including visual acuity (corrected, if applicable) \< 0.8 (due to the use of visual aids) (Freiburg Vision Test, Bach 1996)
  • Person deprived of liberty or under the safeguard of justice
  • Pregnant, parturient or breastfeeding women
  • Subject in a period of exclusion defined by another clinical study.
  • Healthy volunteers only:
  • History of major neurological or psychiatric illness with ongoing psychotropic medication (i.e., antidepressant, thyroid regulator, antipsychotic, benzodiazepine or hypnotic).
  • Patients only:
  • Only patients treated with neuroleptics, whether or not combined with an anti-parkinsonian corrector or anti-depressant, will be included. Patients taking benzodiazepines will be excluded

Key Trial Info

Start Date :

August 12 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 12 2027

Estimated Enrollment :

120 Patients enrolled

Trial Details

Trial ID

NCT04432116

Start Date

August 12 2021

End Date

May 12 2027

Last Update

March 5 2025

Active Locations (1)

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1

Services de Psychiatrie I et II - Pôle de Psychiatrie CHRU Strasbourg

Strasbourg, France, 67091

Time and Virtual Reality in Schizophrenia and Bipolar Disorder | DecenTrialz