Status:
COMPLETED
Fertility Restoration Using Autologous Mesenchymal Stem Cells
Lead Sponsor:
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Collaborating Sponsors:
Belarusian Medical Academy of Post-Graduate Education
Conditions:
Chronic Endometritis
Uterus; Scar
Eligibility:
FEMALE
18-45 years
Phase:
PHASE1
PHASE2
Brief Summary
Treatment of the patients with scarring and adhesions in the uterus resulting from caesarean section or chronic inflammation in the mucosa of the uterus and fallopian tubes and preventing the occurren...
Detailed Description
The aim of the project is to develop a biomedical cell product based on autologous adipose tissue derived mesenchymal stem cells and a biodegradable carrier for highly effective treatment and preventi...
Eligibility Criteria
Inclusion
- chronic endometritis
- postoperative uterus scars
- uterine synechia
- fallopian tube obstruction
- absence of acute inflammation in the uterus
Exclusion
- Patients with genetic diseases of muscle and connective tissue;
- Patients with malformations of the uterus;
- Acute and chronic infectious diseases: HIV, mycoplasma infection, hepatitis B and C, syphilis; autoimmune diseases; oncological diseases; continuous hormonal therapy with cytostatics corticosteroids; acute noncommunicable diseases;
- mental disorders;
- Drug or alcohol addiction;
- Benign tumors of uterus and appendages;
- Hypersensitivity to any component of the studied biomedical cell product.
Key Trial Info
Start Date :
October 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 30 2021
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04432467
Start Date
October 1 2020
End Date
September 30 2021
Last Update
December 10 2021
Active Locations (1)
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1
Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus
Minsk, Belarus, 220072