Status:
COMPLETED
Effects of Crystal Solution and Colloid Solution on Mother and Fetus
Lead Sponsor:
China International Neuroscience Institution
Conditions:
Cesarean Section
Spinal Anesthesia
Eligibility:
FEMALE
20-40 years
Phase:
PHASE4
Brief Summary
Comparison of the effects of crystal solution (lactic acid Ringer's solution) and colloid solution (hydroxyethyl starch) on mother and fetus after cesarean section
Detailed Description
The Hydroxyethl group use 10 ml/kg hydroxyethl starch as well as goal-directed fluid therapy with 3ml/kg hydroxyethl starch. The control group 10 ml/kg Lactated Ringer's solution as well as goal-direc...
Eligibility Criteria
Inclusion
- Healthy singleton pregnancy scheduled for elective cesarean section under CSEA; American Society of Anesthesiologists (ASA) physical status Ⅰ/Ⅱ; Age ranging from 20 to 40 years old.
Exclusion
- History of mental disorder or epilepsy; History of central nervous system (CNS) disease; Preexisting or pregnancy-induced hypertension; History of lumber injury; Severe hypovolemia; Allergy or hypersensitivity to norepinephrine; Body mass index (BMI) above 40 kg/m2; Infection at the puncture site; Tricyclic or imipramine antidepressants.
Key Trial Info
Start Date :
January 30 2022
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 15 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04432675
Start Date
January 30 2022
End Date
November 15 2022
Last Update
December 1 2022
Active Locations (1)
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1
Xuanwu hospital
Beijing, Beijing Municipality, China, 100053