Status:

COMPLETED

Study on the Protective Effect of RIPC in Patients Undergoing Cardiac Surgery.

Lead Sponsor:

Shanghai Zhongshan Hospital

Conditions:

Cardiac Surgery

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

To observe the effect of RIPC on the function of vital organs after cardiac surgery, and to explore its possible mechanism.

Eligibility Criteria

Inclusion

  • patients with aortic valve, mitral valve, tricuspid valve, ascending aortic disease and coronary atherosclerosis who were admitted to hospital for elective valve repair, replacement, artificial vascular replacement or coronary artery bypass grafting.
  • age 18-80 years old.
  • No restriction on gender.
  • ASA grade II\~III.
  • NYHAII\~III level.
  • the patient or his family member has signed the informed consent form for the clinical trial

Exclusion

  • those who are disabled in the selected test.
  • less than 5 years of education.
  • The preoperative left ventricular ejection fraction ((LVEF)) was less than 40%.
  • Myocardial infarction occurred in nearly one month.
  • malignant tumor, hematological disease, severe liver and kidney dysfunction, recent severe infection, etc.
  • History of nervous system, immune system and mental illness.
  • recent operation history of heart, brain, lung, liver, kidney and other important organs

Key Trial Info

Start Date :

September 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 31 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04433468

Start Date

September 1 2020

End Date

March 31 2021

Last Update

July 1 2022

Active Locations (1)

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1

180 Fenglin Road

Shanghai, China, 200032