Status:
UNKNOWN
Nailfold Capillaroscopy Evaluation in Cushing Syndrome Patients
Lead Sponsor:
Marmara University
Conditions:
Cushing Syndrome
Hypercortisolism
Eligibility:
All Genders
18-70 years
Brief Summary
This cross-sectional, single-center study will assess the microvascular function using a nailfold video-capillaroscopy in patients with endogenous Cushing syndrome.
Detailed Description
Endogenous Cushing's syndrome (CS) is associated with increased macrovascular diseases and impaired endothelial function. There is no clear data about the effects of hypercortisolism on microcirculati...
Eligibility Criteria
Inclusion
- Male and female patients diagnosed as Cushing syndrome (CS) caused by ACTH-producing pituitary adenoma or cortisol producing adrenal adenoma
- Age between 18 and 70 years
Exclusion
- Chronic glucocorticoid use
- CS caused by ectopic ACTH producing tumors
- CS caused by adrenocortical carcinoma
- Pseudo CS
- Patients with Raynaud phenomenon
- Patients with collagen tissue disease
- Patients who use drugs that affect the metabolism of fibrinolysis (such as oral contraceptives)
- Employees at work at risk of microtrauma (such as gardeners, farmers)
- Skin diseases with nail fold involvement (such as dermatitis, psoriasis)
Key Trial Info
Start Date :
June 15 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 15 2021
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04433819
Start Date
June 15 2020
End Date
January 15 2021
Last Update
June 16 2020
Active Locations (1)
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1
Marmara University Medical School Section of Endocrinology and Metabolism
Istanbul, Turkey (Türkiye), 34899