Status:

COMPLETED

Association of the Neutrophil/Lymphocyte Ratio With Clinical Complications and Mortality in COVID-19 Patients

Lead Sponsor:

Hospital Regional de Alta especialidad de Ixtapaluca

Collaborating Sponsors:

Hospital General de México Dr. Eduardo Liceaga

Conditions:

Covid-19

Eligibility:

All Genders

Brief Summary

There is little information about the clinical characteristics and risk factors of Covid-19 in Latin American countries considering the ethnic differences and the high prevalence of obesity and cardio...

Detailed Description

Data collection Data was collected deidentified admission from adult patients, with oxygen therapy. Data were extracted from clinical medical records and the electronic database of daily laboratory te...

Eligibility Criteria

Inclusion

  • Adult patients (aged ≥18 years)
  • Clinical (Positive RT-PCR for SARS-CoV-2 test) and radiological diagnosis of pulmonary infection by COVID-19
  • Diagnosis of acute respiratory distress syndrome clinical panel in accordance with Berlin 2012 criteria
  • Need of non-invasive ventilation (NIV or CPAP) or invasive ventilation (intubation)

Exclusion

  • Previous diagnosis of severe liver or kidney failure.
  • Patients with Human Immunodeficiency Virus (HIV) infection.
  • Patients with previous hematological diseases (Leukemia) that condition alterations in blood counts.
  • Consumption of treatments with any type of immunosuppressants prior to admission that conditions low lymphocytes.
  • Patients with a diagnosis of active or non-active cancer.
  • Absence of a clinical record for monitoring the data.
  • Pregnancy.
  • Patients referred from other institutions for their medical care. Clinical records of patients who requested their voluntary discharge Clinical records that do not include information of the course of COVID-19 infection

Key Trial Info

Start Date :

March 28 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

May 5 2020

Estimated Enrollment :

221 Patients enrolled

Trial Details

Trial ID

NCT04434157

Start Date

March 28 2020

End Date

May 5 2020

Last Update

June 16 2020

Active Locations (1)

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Hospital Regional de Alta Especialidad de Ixtapaluca

Ixtapaluca, State of Mexico, Mexico, 56530