Status:

UNKNOWN

Evaluation of Clinical, Radiomics and Molecular Features of Lung Metastasis in PDAC Patients (LUMACA Trial)

Lead Sponsor:

IRCCS San Raffaele

Conditions:

Pancreas Adenocarcinoma

Eligibility:

All Genders

18+ years

Brief Summary

The aim of this study is the characterization from epidemiological, radiomics and molecular point of view of lung metastasis of patients at beginning affected by pancreatic adenocarcinoma (PDAC), whic...

Detailed Description

Radical surgical treatment of primitive PDAC, associated with adjuvant cancer treatments, is possible only in 15-20% of patients, and, to date, represents the best therapeutic strategy. Nevertheless, ...

Eligibility Criteria

Inclusion

  • Cytological/histological diagnosis of pancreatic adenocarcinoma as a primary tumor and localization of adenocarcinoma compatible with pancreatic primitivity for lung metastasis;
  • Previous surgical resection of the primary tumor;
  • Exclusive presence of single or multiple lung metastasis at disease recurrence;
  • Radical or diagnostic excision of lung metastasis;
  • Informed patient consent (for currently living patients).

Exclusion

  • Patients not undergoing lung resection surgery for diagnostic and/or therapeutic purposes for cardiac or respiratory functional contraindication.
  • Patients with lung metastases synchronous with primary cancer. Contacts and Locations

Key Trial Info

Start Date :

May 27 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT04435067

Start Date

May 27 2020

End Date

December 31 2021

Last Update

July 16 2020

Active Locations (4)

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Page 1 of 1 (4 locations)

1

IRCCS San Raffaele Diagnostic Radiology Unit

Milan, Italy, 20132

2

IRCCS San Raffaele Medical Oncology Unit

Milan, Italy, 20132

3

IRCCS San Raffaele Pathological Anatomy Unit

Milan, Italy, 20132

4

IRCCS San Raffaele Thoracic Surgery Unit

Milan, Italy, 20132