Status:

COMPLETED

PET/MRI in the Diagnosis of Pediatric Chronic Pain

Lead Sponsor:

Stanford University

Collaborating Sponsors:

GE Healthcare

Conditions:

Chronic Pain

Pediatric Disorder

Eligibility:

All Genders

11-18 years

Phase:

PHASE1

Brief Summary

\[18F\]FTC-146 is a sigma-1 receptor detector and is an experimental radiotracer. Several studies have implicated involvement of sigma-1 receptors in generation and perpetuation of chronic pain condit...

Detailed Description

It is estimated that 20% to 35% of children and adolescents worldwide are affected by chronic pain. As a result of chronic pain, children may miss school, withdraw from social activities, and develop ...

Eligibility Criteria

Inclusion

  • 11-18 years old.
  • Chronic pain (nociceptive, neuropathic or mixed pain) lasting at least 2 months.
  • Pain level of at least 4/10 on a 0-10 Comparative Pain Scale (reported at time of screening).
  • Covid Vaccination status: Vaccinated or unvaccinated subjects who received a negative test result from the Covid test within 72 hours of the scan.

Exclusion

  • MRI incompatible
  • Pregnant or nursing
  • Non-English speaker
  • Claustrophobic

Key Trial Info

Start Date :

November 19 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 31 2024

Estimated Enrollment :

5 Patients enrolled

Trial Details

Trial ID

NCT04435821

Start Date

November 19 2020

End Date

October 31 2024

Last Update

June 6 2025

Active Locations (1)

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1

Stanford University

Stanford, California, United States, 94305