Status:

COMPLETED

Inflammatory Effect Comparison Between Fentanyl and Remifentanil in Mastectomy Under General Anesthesia

Lead Sponsor:

Udayana University

Conditions:

Breast Disease

Anesthesia

Eligibility:

FEMALE

30-65 years

Phase:

NA

Brief Summary

Mastectomy triggers stress and inflammation responses due to tissue trauma. Surgical stress will increase levels of hormones (adrenocorticotropic hormone, cortisol, antidiuretic hormone, epinephrine, ...

Eligibility Criteria

Inclusion

  • Patients scheduled for a mastectomy under general anesthesia
  • Patients aged 30-65 years old
  • ASA physical status: I-II

Exclusion

  • Refusal to be included in the study
  • History of opioid allergies
  • Long-term use of steroids
  • Patients on β blockers medication
  • History of diabetes, autoimmune disease, or heart disease

Key Trial Info

Start Date :

July 27 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2021

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04435925

Start Date

July 27 2020

End Date

April 30 2021

Last Update

June 2 2021

Active Locations (1)

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Sanglah General Hospital

Denpasar, Bali, Indonesia, 80114