Status:

COMPLETED

Evaluation of Updated Continuous Glucose Monitoring (CGM) Form Factor in Adults, Adolescents and Pediatrics

Lead Sponsor:

Medtronic Diabetes

Conditions:

Type 1 Diabetes Mellitus

Type 2 Diabetes Mellitus

Eligibility:

All Genders

2-80 years

Phase:

NA

Brief Summary

The purpose of this study is to demonstrate the performance of the Disposable Sensor (DS5) in subjects age 2 - 80 years, for the span of 170 hours (7 days).

Detailed Description

The purpose of this study is to demonstrate the performance of the Disposable Sensor (DS5) in subjects age 2 - 80 years, for the span of 170 hours (7 days). This is a multi-center study.

Eligibility Criteria

Inclusion

  • Individual is 2 - 80 years of age at time of enrollment.
  • Subject has a clinical diagnosis of type 1 or type 2 diabetes:
  • If subject is 14-80 years of age, subject has a clinical diagnosis of type 1 or type 2 diabetes for a minimum of 6 months duration as determined via medical record/ source documentation by an individual qualified to make a medical diagnosis.
  • If subject is 2-13 years of age, subject has a clinical diagnosis of type 1 or type 2 diabetes as determined via medical record/ source documentation by an individual qualified to make a medical diagnosis.
  • If subject is participating in YSI™\* FST , subject has adequate venous access as assessed by investigator or appropriate staff.
  • Subjects participating in the high and low glucose challenges must have an insulin carbohydrate ratio(s) and insulin sensitivity factor(s). Subjects without ratios may participate under observation only.

Exclusion

  • Subject will not tolerate tape adhesive in the area of sensor placement as assessed by a qualified individual.
  • Subject has any unresolved adverse skin condition in the area of sensor or device placement (e.g., psoriasis, rash, Staphylococcus infection).
  • Subject is actively participating in an investigational study (e.g., drug or device) wherein he/she has received treatment from an investigational study (drug or device) in the last 2 weeks prior to Visit 1. (Please note participation in an observational study is acceptable.)
  • Subject is female of child-bearing potential and has a pregnancy screening test that is positive.
  • Subject is a sexually active female of child-bearing potential and is not using a form of contraception deemed reliable by investigator.
  • Subject is female and plans to become pregnant during the course of the study.
  • Subject has had a hypoglycemic seizure within the past 6 months prior to enrollment.
  • Subject has had hypoglycemia resulting in loss of consciousness within the past 6 months prior to enrollment.
  • Subject has had an episode of diabetic ketoacidosis (DKA) within the past 6 months prior to enrollment.
  • Subject has a history of a seizure disorder.
  • Subject has central nervous system or cardiac disorder resulting in syncope.
  • Subject has a history of myocardial infarction, unstable angina, coronary artery bypass surgery, coronary artery stenting, transient ischemic attack (TIA), cerebrovascular accident (CVA), angina, congestive heart failure, ventricular rhythm disturbances or thromboembolic disease
  • If subject is 7-80 years of age, subject has a hematocrit (Hct) more than 10% below the lower limit of normal reference range (please note that patients may use prior blood draw from routine care as long as done within 6 months of screening and report of lab placed with subject source documents).
  • Subject has a history of adrenal insufficiency.
  • Subject is a member of the research staff involved with the study.

Key Trial Info

Start Date :

July 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 12 2022

Estimated Enrollment :

317 Patients enrolled

Trial Details

Trial ID

NCT04436822

Start Date

July 15 2020

End Date

April 12 2022

Last Update

June 2 2023

Active Locations (18)

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Page 1 of 5 (18 locations)

1

AMCR Institute

Escondido, California, United States, 92025

2

Sansum Diabetes Research Institute

Santa Barbara, California, United States, 93105

3

SoCal Diabetes

Torrance, California, United States, 90505

4

Diablo Clinical Research, Inc.

Walnut Creek, California, United States, 94598