Status:

COMPLETED

Multiparametric Photoacoustic Imaging in the Course of Radiation Therapy of Malignant Head and Neck Tumors

Lead Sponsor:

University Hospital Heidelberg

Conditions:

Head and Neck Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Multispectral photoacoustic imaging enables the measurement of the optical absorption of various tissue components or exogenous contrast agents in vivo. The dominant, near infrared absorbing chromopho...

Detailed Description

Multispectral photoacoustics enable non-invasive, inexpensive and dose-free real-time imaging of light-absorbing molecules (absorbers), e.g. Deoxyhemoglobin and oxygenated hemoglobin in human tissue. ...

Eligibility Criteria

Inclusion

  • Willingness and ability to participate
  • sufficient knowledge of German to understand the patient / subject information and the declaration of consent,
  • tumor disease to be treated by radiotherapy in the neck and neck area,
  • Completed wound healing after operative interventions in the head and neck area,
  • The patient's consent and written consent,
  • the patient's ability to assess the nature and scope as well as possible consequences of the clinical study,
  • 8\. Age ≥ 18 years.
  • Requirement 3 does not apply to the control group of healthy subjects

Exclusion

  • Pre-radiation in the head and neck area
  • Inadequate regression of toxicities from previous therapies
  • Indications that the participant is unlikely to adhere to the study protocol (e.g. lack of compliance)
  • Missing written declaration of consent

Key Trial Info

Start Date :

July 9 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2023

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04437030

Start Date

July 9 2020

End Date

July 1 2023

Last Update

January 5 2024

Active Locations (1)

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University Hopsital Heidelberg

Heidelberg, Germany, 69120

Multiparametric Photoacoustic Imaging in the Course of Radiation Therapy of Malignant Head and Neck Tumors | DecenTrialz