Status:

COMPLETED

eIMPACT-DM Pilot Trial: Depression Treatment to Reduce Diabetes Risk

Lead Sponsor:

Indiana University

Collaborating Sponsors:

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Depression

Major Depressive Disorder

Eligibility:

All Genders

18+ years

Phase:

PHASE2

Brief Summary

This pilot randomized controlled trial seeks: (1) to determine the preliminary efficacy of our modernized collaborative care intervention for depression in improving the diabetes risk markers of hemog...

Detailed Description

Diabetes affects 31 million (12%) U.S. adults, and another 82 million (34%) adults have prediabetes, a precursor to diabetes. The ramifications of diabetes are grave and include cardiovascular disease...

Eligibility Criteria

Inclusion

  • Current primary care patient in Eskenazi Health
  • Age ≥18 years
  • Depressive disorder at screening
  • Prediabetes at screening

Exclusion

  • History of type 1 or type 2 diabetes
  • Major inflammatory conditions: HIV/AIDS, chronic kidney disease, systemic inflammatory disease (e.g., rheumatoid arthritis, lupus, Crohn's disease, and ulcerative colitis), or active cancer/current cancer treatment
  • Current pregnancy
  • Severe cognitive impairment
  • Acute risk of suicide
  • History of bipolar disorder or psychosis or current use of an atypical antipsychotic medication:
  • Participation in our prior eIMPACT Trial

Key Trial Info

Start Date :

October 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

August 29 2022

Estimated Enrollment :

46 Patients enrolled

Trial Details

Trial ID

NCT04437485

Start Date

October 14 2020

End Date

August 29 2022

Last Update

November 2 2023

Active Locations (1)

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IUPUI Department of Psychology

Indianapolis, Indiana, United States, 46202