Status:

ENROLLING_BY_INVITATION

Long-Term Follow-up of Subjects With Fanconi Anaemia Subtype A Treated With ex Vivo Gene Therapy

Lead Sponsor:

Rocket Pharmaceuticals Inc.

Conditions:

Fanconi Anemia Complementation Group A

Fanconi Anemia

Eligibility:

All Genders

Brief Summary

This is a long-term safety and efficacy follow-up study for subjects with Fanconi Anaemia Subtype A who have been treated with ex vivo gene therapy on the FANCOLEN-I trial. After completion of the FAN...

Detailed Description

This long-term follow-up protocol will evaluate the long term safety and efficacy of the infusion of autologous CD34+ cells transduced with lentiviral vector (LV) carrying the FANCA gene.

Eligibility Criteria

Inclusion

  • Enrolled in the FANCOLEN-I study
  • Treated with gene therapy in the FANCOLEN-I study
  • Able to adhere to the study visit schedule and protocol requirements
  • Provided written informed consent and, as applicable, assent to participate

Exclusion

  • There are no exclusion criteria for this study

Key Trial Info

Start Date :

June 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 30 2035

Estimated Enrollment :

9 Patients enrolled

Trial Details

Trial ID

NCT04437771

Start Date

June 1 2020

End Date

January 30 2035

Last Update

June 22 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Hospital Infantil Universitario Niño Jesús (HIUNJ)

Madrid, Spain, 28009

Long-Term Follow-up of Subjects With Fanconi Anaemia Subtype A Treated With ex Vivo Gene Therapy | DecenTrialz