Status:
COMPLETED
Activation of miRNA and Proteins After Acute Experimental Pain. (miRNA: Micro RNA)
Lead Sponsor:
Aalborg University
Conditions:
Hypertonic Saline
Isotonic Saline
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
In this experiment, the investigators would like to test the following: 1. Does acute pain induced by hypertonic injection cause changes in plasma miRNA and protein expression ? 2. Can these canges c...
Eligibility Criteria
Inclusion
- Healthy men and women in the age 18-80 years
- Speak and understand English
Exclusion
- Acute and chronic pain
- Pregnancy or breastfeeding
- Drug addiction defined as the use of cannabis, opioids or other drugs
- Present or previous history of neurological, dermatological, immunological, musculoskeletal, cardiac disorder or mental illnesses that may affect the results (e.g. Neuropathy, muscular pain in the upper extremities, etc.)
- Lack of ability to cooperate
- Current use of medications that may affect the trial, such as antipsychotics and pain killers as well as systemic or topical steroids and anti-inflammatory drugs.
- Skin diseases
- Consumption of alcohol or painkillers 24 hours before the study days and between these
- Participation in other trials within 1 week of study entry (4 weeks in the case of pharmaceutical trials)
Key Trial Info
Start Date :
November 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2022
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04439994
Start Date
November 1 2020
End Date
July 1 2022
Last Update
October 3 2023
Active Locations (2)
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1
Aalborg University
Aalborg, North Denmark, Denmark, 92200
2
AAlborg University
Aalborg, North Denmark, Denmark, 9220