Status:
COMPLETED
Factors Associated with Falling in Parkinson's Disease
Lead Sponsor:
University Hospital, Ghent
Collaborating Sponsors:
University Ghent
Conditions:
Parkinson Disease
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The objective of this study will be to identify multidisciplinary fall risk factors in persons with stage 3 idiopathic Parkinson's Disease compared to age and sex-matched healthy adults. Both the rela...
Eligibility Criteria
Inclusion
- Parkinson's Disease group
- Inclusion criteria:
- Persons with idiopathic PD diagnosed by a medical doctor according to the United Kingdom PD Brain Bank Criteria
- Aged between 18 and 75 years-old
- Stage 3 on the Hoehn and Yahr scale in the on-medication state
- On a stable dose of PD medication (at least one week)
- Able to stand and walk on a treadmill without support for at least 3 minutes
- Able to give consent
- Exclusion criteria:
- Atypical parkinsonism
- Unpredictable symptom fluctuations
- Previous surgical management of PD (i.e., deep brain stimulation surgery; pallidotomy)
- Duodopa pump therapy
- Dementia (Montreal Cognitive Assessment (MoCA) \< 21)\[1\]
- Symptomatic orthostatic hypotension (e.g. frequent syncope episodes)
- Concurrent neurological disorders (e.g. stroke)
- Comorbidities that affect gait or balance (e.g. peripheral neuropathy)
- Acute illness
- Epilepsy or history of seizures
- Depression (MDS-UPDRS item 1.3 ≥ 2)
- Body weight over 120 kilograms
- Pregnancy
- Participation in other ongoing experimental trials
- Healthy control group
- Inclusion criteria:
- Age and sex-matched healthy adults
- Exclusion criteria:
- Symptomatic orthostatic hypotension (e.g. frequent syncope episodes)
- Body weight over 120 kilograms
- Pregnancy
- Participation in other ongoing experimental trials
Exclusion
Key Trial Info
Start Date :
October 12 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2023
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT04440033
Start Date
October 12 2020
End Date
December 1 2023
Last Update
September 19 2024
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Ghent University Hospital
Ghent, Belgium, 9000
2
Ghent University
Ghent, Belgium, 9000