Status:
COMPLETED
Evaluation of Cutaneous and Circulating Inflammatory Biomarkers in Hidradenitis Suppurativa and Atopic Dermatitis
Lead Sponsor:
Kymera Therapeutics, Inc.
Collaborating Sponsors:
York Dermatology Clinic and Research Centre
Conditions:
Hidradenitis Suppurativa
Dermatitis, Atopic
Eligibility:
All Genders
18+ years
Brief Summary
This non-intervention study will identify the biomarker profiles in hidradenitis suppurativa (HS) and atopic dermatitis (AD) (as a comparator) that would have the most utility in interventional studie...
Detailed Description
This study is an exploratory correlative study in subjects with HS or AD. Blood samples and skin biopsies will be collected from all subjects and used to assess the following: cutaneous and circulatin...
Eligibility Criteria
Inclusion
- Age 18 or older
- Active HS or AD disease, diagnosed by PI
- Patients with mild (HS only), moderate, or severe disease using the HS-PGA or PGA assessment.
- Must sign an informed consent form (ICF) indicating that he or she understands the purpose of and procedures required for the study, and is willing to participate in the study.
Exclusion
- Patient is currently on a biologic or other immunosuppressive treatment for HS or AD.
- Use of biologic treatment for HS or AD within 3 months or 5 half-lives, whichever is longer
- Use of non-biologic immunosuppressive treatment (eg. Cyclosporin) in the last 4 weeks.
Key Trial Info
Start Date :
May 28 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 24 2021
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04440410
Start Date
May 28 2020
End Date
March 24 2021
Last Update
April 13 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
York Dermatology Clinic and Research Centre
Richmond Hill, Ontario, Canada, L4C 9M7