Status:
COMPLETED
Gut Microbiome of Patients Undergoing Antibiotic Therapy for Orthopedic Device-related Infection
Lead Sponsor:
AO Research Institute Davos
Conditions:
Fractures, Bone
Infection, Bacterial
Eligibility:
All Genders
18+ years
Brief Summary
The microbiome of 80 orthopedic-device related infection (ODRI) patients treated with antibiotics and 10 healthy controls will be investigated. Samples (blood, stool, saliva, skin-swab) are collected ...
Eligibility Criteria
Inclusion
- The patient is planned to undergo revision surgery due to suspected bone or joint infection.
- The patient is at least 18 years old
Exclusion
- The patient took antibiotics in the previous six weeks of recruitment (a single dose/"shot" of antibiotics during this period is not considered).
- The patient suffers from gut-associated morbidities such as Morbus Crohn or colitis ulcerosa.
- The patient suffers from psychiatric disorders/cognitive impairment affecting understanding.
- The patient is unable to give consent and follow procedures and/or has insufficient knowledge of the project language.
Key Trial Info
Start Date :
November 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 31 2022
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT04440631
Start Date
November 1 2019
End Date
December 31 2022
Last Update
February 3 2023
Active Locations (2)
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1
Universitätsspital Basel
Basel, Switzerland, 4031
2
Schulthess Klinik Zürich
Zurich, Switzerland, 8008