Status:
UNKNOWN
Lignocaine Nebulization for Attenuation of Intubation Stress Response
Lead Sponsor:
Assiut University
Conditions:
Pressor Response
Eligibility:
FEMALE
18-45 years
Phase:
PHASE4
Brief Summary
To study the effect of lignocaine nebulization on attenuation of the pressor response during induction and emergence of anesthesia in patients with severe pre-eclampsia
Detailed Description
The pressor response to laryngoscopy and tracheal intubation is a very important issue in hypertensive pregnant patients that can lead to increased maternal intracranial pressure, cerebral haemorrhage...
Eligibility Criteria
Inclusion
- American Society of Anesthesiologist (ASA) II , III with severe pre-eclampsia
- Scheduled for caesarean deliveries under general anesthesia
Exclusion
- severe obesity (BMI ≥ 40 )
- Cardiac patients
- History of diabetes
- Renal dysfunction (Elevated creatinine ≥ 2 mg\\dl)
- Hepatic dysfunction (Elevated hepatic enzymes three times above normal value)
- Known fetal anomalies
Key Trial Info
Start Date :
February 24 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 23 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04441073
Start Date
February 24 2021
End Date
February 23 2022
Last Update
January 19 2022
Active Locations (1)
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1
Assiut University
Asyut, Egypt, 71515