Status:
COMPLETED
Glutamine With Topical Corticosteroids for Lichen Planus Treatment
Lead Sponsor:
Hams Hamed Abdelrahman
Conditions:
Lichen Penis Planus
Eligibility:
All Genders
30-60 years
Phase:
NA
Brief Summary
Lichen planus (LP) is an inflammatory skin disease of unknown etiology. Glutamine promotes protein and collagen synthesis, imparts immunity, and maintains the alimentary canal mucosa structure.
Detailed Description
Lichen planus (LP) is an inflammatory skin disease of unknown etiology. Recently, increased oxidative stress has been implicated in the pathogenesis of erosive oral lichen planus (EOLP). Glutamine is ...
Eligibility Criteria
Inclusion
- Patients clinically and histopathologically diagnosed to be suffering from EOLP.
- Patients who had symptoms i.e. pain and/or burning sensation secondary to EOLP.
- Patients under stressful life conditions as evidenced by ISMA-UK Stress Questionnaire
- Males and Females with an age ranging from 30-60years
Exclusion
- Patients suspected to have a lichenoid drug reaction or lichenoid contact allergy.
- Patients suffering from any systemic diseases (such as diabetes, cardiovascular, liver disorder, renal dysfunction)
- Patients with findings of any physical or mental abnormality which would interfere with or be affected by the study procedure.
Key Trial Info
Start Date :
April 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2020
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04442633
Start Date
April 1 2019
End Date
January 1 2020
Last Update
June 22 2020
Active Locations (1)
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1
Outpatient Clinic of Oral medicine Department, Faculty of Dentistry, Alexandria University, Egypt
Alexandria, Egypt