Status:

COMPLETED

Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation

Lead Sponsor:

Peking University Third Hospital

Conditions:

Adolescent

Adult

Eligibility:

All Genders

18-45 years

Brief Summary

To observe the retinal microvascular alteration during 3 months follow-up after Implantable Collamer Lens (ICL) operation in moderate and high myopia patients using quantitative optical coherence tomo...

Detailed Description

The study object is moderate and high myopia patients, underwent ICL implantation. OCTA was used to image the superficial and deep retinal vascular plexuses before ICL implantation surgery and at 3 mo...

Eligibility Criteria

Inclusion

  • 18 to 45 years old;
  • Binocular myopia, with a refraction of greater than -3 diopters (D);
  • anterior chamber depth (ACD, measured from the endothelium to the crystalline lens) \> 2.8 mm;
  • corneal endothelial cell count (cECC) ≥ 2000 cells/mm2;
  • stable refraction at least 1 year before surgery;
  • unsatisfactory vision with contact lenses or spectacles.

Exclusion

  • history of intraocular surgery
  • other ocular pathology (uveitis, glaucoma, cataract, keratoconus, severe dry eye, etc.)
  • other serious systemic disease (diabetes, uncontrolled hypertension, severe hyperthyroidism, etc.).

Key Trial Info

Start Date :

November 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2019

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT04443231

Start Date

November 1 2018

End Date

October 1 2019

Last Update

June 23 2020

Active Locations (1)

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Peking University Third Hospital

Beijing, Beijing Municipality, China, 100191