Status:
UNKNOWN
Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients
Lead Sponsor:
CMN "20 de Noviembre"
Conditions:
COVID-19
Eligibility:
All Genders
18-59 years
Phase:
PHASE1
Brief Summary
The primary objective of this study is to evaluate the efficacy and security of chloroquine phosphate prophylactic use for reducing the risk of infection by severe acute respiratory syndrome coronavir...
Detailed Description
Health Care Workers as first line of hospital care, are at high risk of infection by severe acute respiratory syndrome coronavirus-2 due for the exposure to COVID-19 patients. The pharmacological trea...
Eligibility Criteria
Inclusion
- Health Care Workers as first line of hospital care exposed to COVID-19 patients.
- Initial polymerase chain reaction assay negative test for severe acute respiratory syndrome coronavirus-2 infection.
- Both sexes
- Agree to participate in the study after signing an informed consent letter.
Exclusion
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with history of heart disease, arrhythmias or QT segment prolongation.
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with liver or kidney disease of any etiology.
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with retinopathy of any etiology.
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with allergy to chloroquine.
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with a history or diagnosis of psoriasis.
- Health Care Workers as first line of hospital care exposed to COVID-19 patients with important primary clinical alterations: renal (creatinine\> 3), liver (Alanine Aminotransferase and Aspartate Aminotransferase x 3), endocrine, neurological.
Key Trial Info
Start Date :
July 27 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 31 2021
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04443270
Start Date
July 27 2020
End Date
January 31 2021
Last Update
July 14 2020
Active Locations (1)
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1
Centro Médico Nacional "20 de Noviembre"
Mexico City, Benito Juárez, Mexico, 03229