Status:
COMPLETED
Comparison of Esophageal and Central Venous Pressure for Estimating Transpulmonary Pressure Changes
Lead Sponsor:
University of Siena
Conditions:
Mechanical Ventilation
Acute Respiratory Distress Syndrome
Eligibility:
All Genders
18-90 years
Brief Summary
Central venous pressure (CVP) is characterized by a low-frequency pleural-dependent as well as a high-frequency cardiac pulsatile component. The aim of the study is to compare the low-frequency compon...
Detailed Description
The investigators will enroll mechanically ventilated patients admitted to the intensive care unit with the diagnosis of respiratory failure monitored with a dedicated nasogastric catheter and a centr...
Eligibility Criteria
Inclusion
- adult patients receiving invasive mechanical ventilation
- diagnosis of acute respiratory failure (defined as the ratio of partial oxygen pressure and fraction of inspired oxygen below 200 mmHg)
- esophageal balloon catheter
- central venous catheter
Exclusion
- age under 18 years old
- Hemodynamic instability
- Esophageal diseases (varices, stenosis..)
- Refusal of the patient
- evidence of active air leak from the lung (pneumothorax, pneumomediastinum, existing chest tube....)
- history of lung/abdominal surgery
- pregnancy
- severe coagulopathy
Key Trial Info
Start Date :
May 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2019
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04443491
Start Date
May 1 2016
End Date
March 1 2019
Last Update
June 23 2020
Active Locations (1)
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1
Azienda Ospedaliera Universitaria Senese
Siena, Italy, 53100