Status:

UNKNOWN

Clinical and Radiograhic Evaluation of NIPSA With and Without Allograft Plus Platelet Rich Fibrin in the Treatment of Intraosseous Defects in Stage III Periodontitis Patients

Lead Sponsor:

Cairo University

Conditions:

Periodontitis Chronic Generalized Severe

Intrabony Periodontal Defect

Eligibility:

All Genders

20-70 years

Phase:

NA

Brief Summary

Several minimal invasive techniques have been proposed since the last decade aiming to enhance and provide adequate environment for periodontal regeneration. Harrel and Rees proposed minimally invasiv...

Detailed Description

Intraosseous vertical defects are one of the consequences that could result from periodontitis, which are classified according to their architecture by the number of residual walls, defect width as we...

Eligibility Criteria

Inclusion

  • Patients with Stage III periodontitis patient having at least one tooth with two wall or combined two to three walled intraosseous defect more than or equal 3 mm deep (assessed by trans-gingival probing, radiographic examination) with clinical attachment level (CAL) more than or equal 5mm and pocket depth (PD) more than or equal 6 mm.
  • Defect not extending to a root furcation area.
  • Vital teeth
  • No history of intake of antibiotics or other medications affecting the periodontium in the previous 6 months.
  • No surgical periodontal therapy carried out in the past 6 months.
  • Able to sign an informed consent form.
  • Patients who are cooperative, motivated, and hygiene conscious.
  • Able to come for the follow up appointment's needed.

Exclusion

  • Any systemic disease that contra-indicates periodontal surgery or may affect healing.
  • Smokers
  • Pregnant females
  • Drug abusers

Key Trial Info

Start Date :

September 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 1 2023

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT04444063

Start Date

September 1 2020

End Date

October 1 2023

Last Update

June 23 2020

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