Status:
TERMINATED
The Malaria Heart Disease Study
Lead Sponsor:
University Hospital, Gentofte, Copenhagen
Collaborating Sponsors:
Federal University of Acre
University of Sao Paulo
Conditions:
Plasmodium Falciparum
Plasmodium Vivax
Eligibility:
All Genders
18+ years
Brief Summary
The Malaria Heart Disease Study is a prospective longitudinal cohort study of a random sample of approximately 1200 individuals from the state of Acre in Brazil. The overall hypothesis is that patient...
Detailed Description
The purpose of this study is to investigate the relationship between exposure to malaria and the risk of developing subclinical and manifest cardiovascular disease. The study is conducted in the high ...
Eligibility Criteria
Inclusion
- Group 1 (History of malaria) Inclusion: Patients with a record of malaria \>=18 years old will be invited at random Exclusion: Persons not able to cooperate and persons unwilling or unable to understand and sign "informed consent", persons who are hospitalized due to severe malaria
- Group 2 (Controls) Inclusion: Patients with no record of malaria \>=18 years old will be invited at random Exclusion: Persons not able to cooperate and persons unwilling or unable to understand and sign "informed consent"
- Group 3 (Symptomatic malaria) Inclusion: Patients \>=18 years old diagnosed in outpatient/inpatient clinic with malaria infection by thick and thin blood smear and/or rapid diagnostic test. Enrollment of both severe (complicated) and uncomplicated malaria cases as defined by the WHO criteria. Exclusion: Persons not able to cooperate and persons unwilling or unable to understand and sign "informed consent", suspected or verified concomitant protozoal infections
Exclusion
Key Trial Info
Start Date :
June 21 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 25 2021
Estimated Enrollment :
597 Patients enrolled
Trial Details
Trial ID
NCT04445103
Start Date
June 21 2020
End Date
January 25 2021
Last Update
July 19 2022
Active Locations (1)
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1
Philip Brainin
Cruzeiro do Sul, Acre, Brazil, 69980000