Status:

UNKNOWN

Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19 and High Risk of Acute Kidney Injury

Lead Sponsor:

Guy's and St Thomas' NHS Foundation Trust

Collaborating Sponsors:

Harvard Medical School (HMS and HSDM)

Conditions:

COVID

Acute Kidney Injury

Eligibility:

All Genders

18+ years

Brief Summary

The aim is to describe the epidemiology and determine the independent risk factors for mortality and acute organ injury in AKI and to assess the impact of different treatment strategies on survival. T...

Detailed Description

Since the outbreak of coronavirus disease 2019 (COVID-19) began in December 2019 in China, over 1 million people have been infected and over 55,000 have died worldwide, and these numbers continue to r...

Eligibility Criteria

Inclusion

  • Adults (aged ≥18 years)
  • Confirmed diagnosis of COVID-19
  • Hospitalized in the ICU for illness related to COVID-19
  • Any of the following:
  • Current in-patient in ICU
  • Previous in-patient in ICU and died in ICU or hospital
  • Previous in-patient in ICU and discharged from ICU alive

Exclusion

  • Younger than 18 years old
  • On chronic dialysis within the last year or on dialysis at ICU admission
  • Functioning kidney transplant
  • No creatinine within 48 hours of ICU admission

Key Trial Info

Start Date :

June 20 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2022

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04445259

Start Date

June 20 2020

End Date

December 31 2022

Last Update

August 4 2021

Active Locations (1)

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1

Guy's & St Thomas' Hospital

London, United Kingdom, SE1 7EH