Status:

UNKNOWN

Hepatobiliary Tumors Tissue Samples Acquisition

Lead Sponsor:

Peking Union Medical College Hospital

Collaborating Sponsors:

OrigiMed

GeneCast Biotechnology Co., Ltd.

Conditions:

Hepatocellular Carcinoma

Cholangiocarcinoma

Eligibility:

All Genders

18+ years

Brief Summary

Hepatobiliary tumors have a poor prognosis and high individual heterogeneity, so it is of great significance to find important prognostic markers and then screen out specific subgroups of people; mean...

Detailed Description

OBJECTIVES: 1. Observe the biomarkers of resectable hepatobiliary tumor recurrence (DFS) and survival (OS); 2. Observe the evolution of tumors and discover specific diagnostic markers as a control gr...

Eligibility Criteria

Inclusion

  • Be older than 18 years old;
  • ECOG 0-2 points;
  • May have received treatment;
  • Clinical consideration or diagnosis of benign and malignant hepatobiliary tumors; or chronic hepatitis, cirrhosis, or healthy control participants;
  • Patients may have received or are about to undergo surgery, chemotherapy, radiotherapy, targeted therapy, local therapy, immunotherapy, etc.;
  • Patients understand and are willing to sign written informed consent documents.

Exclusion

  • The doctor thinks it is not suitable to enter the group (mental disorder or poor compliance, etc.)
  • Pregnant women;
  • Active or uncontrollable infections (fungi, bacteria, etc.);
  • Estimated survival time \<12 weeks;
  • If the patient is receiving chronic anticoagulant therapy, the anticoagulant withdrawal should not be shorter than 3 days;
  • In the evaluation of the doctor, there is a risk of uncontrolled complications in the biopsy.

Key Trial Info

Start Date :

October 11 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2025

Estimated Enrollment :

450 Patients enrolled

Trial Details

Trial ID

NCT04445532

Start Date

October 11 2020

End Date

June 1 2025

Last Update

July 7 2023

Active Locations (1)

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1

Chinese Academy of Medical Sciences & Peking Union Medical College Hospital

Beijing, Beijing Municipality, China, 100730