Status:

COMPLETED

The Effect of a Probiotic Strain on Ibuprofen-induced GI Damage

Lead Sponsor:

Chr Hansen

Conditions:

Reduction of Small Intestinal Ulceration Risk

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

To investigate if a daily dose of minimum 15 billion CFU of Bif195 reduces the risk of small-intestinal tissue damage in an Ibuprofen challenge model as assessed by video capsule endoscopy in a health...

Detailed Description

This trial is a single-site, randomized, double-blind, placebo-controlled, two-armed, parallel-group trial in healthy volunteers aged 18 - 40 years. The trial will investigate the effect of daily inta...

Eligibility Criteria

Inclusion

  • Written informed consent
  • Healthy and without any gastrointestinal pain or other significant symptoms
  • Age 18 - 40 years
  • Willing to abstain from any other probiotic products and/or medication known to alter gastrointestinal function throughout the participation of the trial

Exclusion

  • \-

Key Trial Info

Start Date :

June 22 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 10 2021

Estimated Enrollment :

177 Patients enrolled

Trial Details

Trial ID

NCT04447924

Start Date

June 22 2020

End Date

June 10 2021

Last Update

August 26 2021

Active Locations (1)

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Atlantia Food Clinical Trials

Chicago, Illinois, United States, 60611