Status:
COMPLETED
Dynamics of Drug Resistance-associated Mutations in HIV-1 DNA Reverse Transcriptase Clearance During Effective Antiretroviral Therapy
Lead Sponsor:
Association de Recherche en Virologie et Dermatologie
Collaborating Sponsors:
ViiV Healthcare
Conditions:
HIV-1-infection
Eligibility:
All Genders
18+ years
Brief Summary
In view of the prolongation of patients living with HIV's life expectancy, the question of optimization of ART, which is still a life-long treatment, becomes central. While most patients achieve virol...
Eligibility Criteria
Inclusion
- HIV-1 infected
- Age ≥ 18 years
- Genotypic resistance test performed at time of failure and harboring at least M184V
- Fully suppressed HIV viral load for at least 5 or 10 years.
- Triple therapy or 2 drug regimen during the entire follow-up
- Availability of at least 1 stored whole blood sample /year
Exclusion
- No genotypic resistance test available at time of failure.
Key Trial Info
Start Date :
July 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 1 2021
Estimated Enrollment :
79 Patients enrolled
Trial Details
Trial ID
NCT04448158
Start Date
July 1 2020
End Date
July 1 2021
Last Update
February 10 2023
Active Locations (1)
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1
ARVD
Paris, France