Status:
COMPLETED
Brain Activity Changes Following Neuroproprioceptive Physiotherapy in Multiple Sclerosis
Lead Sponsor:
Charles University, Czech Republic
Conditions:
Neuronal Plasticity
Multiple Sclerosis
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Imaging methods bring new possibilities for describing the brain plasticity processes that underly the improvement of clinical function after physiotherapy in people with multiple sclerosis (pwMS). Th...
Detailed Description
The study was designed as parallel group randomized comparison of two kinds of physiotherapeutic interventions referred to healthy controls. MS patients were examined by fMRI (primary outcomes) and c...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- definite MS
- stable clinical status in the preceding 3 months
- imuno-modulatory treatment for at least two years (including glatiramer acetate, interferon beta-1a, 1b, mitoxantrone, fingolimod, natulizumab)
- Expanded Disability Status Scale (EDSS)≤6
- predominant motor impartment
- six months or more without any physiotherapy
- ability to undergo ambulatory physiotherapy
- Exlusion criteria:
- other neurological disease or conditions disabling movement
Exclusion
Key Trial Info
Start Date :
May 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 10 2019
Estimated Enrollment :
87 Patients enrolled
Trial Details
Trial ID
NCT04448444
Start Date
May 1 2015
End Date
November 10 2019
Last Update
June 29 2020
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