Status:
COMPLETED
Chest Wall Deformities in Children - Epidemiological Data
Lead Sponsor:
Universitätsklinikum Hamburg-Eppendorf
Conditions:
Chest Wall Deformity
Funnel Chest
Eligibility:
All Genders
6-30 years
Brief Summary
Pectus excavatum (PE) or funnel breast is the most common congenital deformity of the chest wall, which occurs in about 1 in 400 births with a boy to girl ratio of 4: 1 to 3: 1. The etiology of PE is ...
Detailed Description
Previous studies suggest that sulfation of proteoglycans plays a crucial role in the normal development of cartilage and bone and could therefore be crucial in the genesis of the disease. The main cat...
Eligibility Criteria
Inclusion
- . All patients who are in the Altona Children's Hospital or in the University Hospital Hamburg. Funnel breast, keel breast, sternal cleft
- . A signed declaration of consent from the parents or legal guardians is available
- . The patient has given a declaration of consent
Exclusion
- Confirmation of another diagnosis associated with chest wall deformities:
- Marfan syndrome
- Noonan syndrome
- Poland syndrome
- Moebius syndrome
- Cantrell Pentalogy
- PHACE association
Key Trial Info
Start Date :
September 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2020
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT04448574
Start Date
September 1 2019
End Date
June 1 2020
Last Update
December 7 2021
Active Locations (2)
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1
University Hospital Hamburg Eppendorf - Department of pediatric surgery
Hamburg, Germany, 20246
2
The Altona Children's Hospital
Hamburg, Germany, 22763