Status:
RECRUITING
Immune Homeostasis in Sepsis and Septic Shock
Lead Sponsor:
Charles University, Czech Republic
Conditions:
Sepsis
Immunologic Paralysis
Eligibility:
All Genders
18+ years
Brief Summary
Detailed description of immune response and its dynamics in sepsis and septic shock patiens by means of transcriptomics, flow-cytometry and cytokine analysis.
Eligibility Criteria
Inclusion
- sepsis/septic shock (SEPSIS-3)
- age ≥18
- informed consent
- inclusion within first 24hrs after development/diagnosis of septic shock
Exclusion
- disagreement of the patient or legal representative with the entry into the study
- patients with primary or secondary immunodeficiency
- presence of active haematological malignancy or an active non-haematological malignancy
Key Trial Info
Start Date :
September 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2027
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04448951
Start Date
September 1 2020
End Date
December 31 2027
Last Update
August 21 2024
Active Locations (1)
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1
Medical ICU, 1st Dept. of Internal Medicine, Teaching Hospital in Pilsen
Pilsen, Česká Republika, Czechia, 330 01