Status:
UNKNOWN
Antinociceptive Effect of Transauricular Electrical Vagal Nerve Stimulation
Lead Sponsor:
University Medicine Greifswald
Conditions:
Pain, Acute
Eligibility:
All Genders
19-40 years
Phase:
NA
Brief Summary
This investigation is going to study whether electrical tVNS applied at the cymba of auricular conchae reduces central sensitization of experimentally induced pain in comparison with electrical sham s...
Eligibility Criteria
Inclusion
- healthy volunteers aged 18-45 years old, who have given informed consent
- at least two days free from consume of recreational drugs
- no local infection at the site of tVNS and pain stimulation
Exclusion
- psychiatric disorders
- abnormal skin conditions (infection, scars, psoriasis, eczema) at the site of tVNS
- contra-indications for MRI (e.g. claustrophobia, pregnancy, tattoos, metallic implants)
- history of coronary heart disease, cardiac arrhythmia, glaucoma, allergy to sulphates
Key Trial Info
Start Date :
May 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2023
Estimated Enrollment :
66 Patients enrolled
Trial Details
Trial ID
NCT04448990
Start Date
May 1 2021
End Date
August 1 2023
Last Update
June 26 2020
Active Locations (1)
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1
University Medicine of Greifswald
Greifswald, Germany, 17475