Status:

COMPLETED

Effects of Continuous Infusion of Intravenous Nefopam on Postoperative Pain and Opioid Consumption After VATS

Lead Sponsor:

Seoul National University Hospital

Collaborating Sponsors:

Pharmbio Korea

Conditions:

Postoperative Pain

Eligibility:

All Genders

19-70 years

Phase:

NA

Brief Summary

This prospective, randomized, double-blinded study is designed to evaluate the postoperative analgesic effect of the continuous infusion of intravenous nefopam in patients undergoing video-assisted th...

Detailed Description

Adult patients undergoing elective unilateral VATS segmentectomy or lobectomy are randomly allocated to receive continuous nefopam infusion (n=45) or not (n=45), in addition to a standard postoperativ...

Eligibility Criteria

Inclusion

  • Patients scheduled to undergo elective unilateral VATS segmentectomy or lobectomy under general anesthesia
  • American Society of Anesthesiologists (ASA) physical classification I-II
  • Consent to IV-patient controlled analgesia use
  • Willingness and ability to sign an informed consent document

Exclusion

  • Do not understand our study
  • Allergies to anesthetic or analgesic medications
  • Continuous local anesthetics infiltration for postoperative pain control
  • Patients who receive mechanical ventilation more than 2 hours after surgery
  • Pregnancy/Breast feeder
  • Medical or psychological disease that can affect the treatment response

Key Trial Info

Start Date :

July 30 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 10 2021

Estimated Enrollment :

90 Patients enrolled

Trial Details

Trial ID

NCT04450355

Start Date

July 30 2020

End Date

November 10 2021

Last Update

May 6 2022

Active Locations (1)

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1

Seoul National University Hospital

Seoul, South Korea, KS013

Effects of Continuous Infusion of Intravenous Nefopam on Postoperative Pain and Opioid Consumption After VATS | DecenTrialz