Status:

RECRUITING

High Flow Nasal Cannula in Pediatric Patients After Cardiothoracic Surgery

Lead Sponsor:

Osaka University

Collaborating Sponsors:

Osaka Women's and Children's Hospital

Hyogo Prefectural Kobe Children's Hospital

Conditions:

Pediatric Patients After Cardiothoracic Surgery

Eligibility:

All Genders

Up to 2 years

Phase:

NA

Brief Summary

High flow nasal cannula(HFNC) ventilation can provide such effects as wash-out effect of the carbon dioxide inside the anatomical dead space,some level of continuous airway pressure and humidified oxy...

Detailed Description

The multi-center RCT will enroll 380 pediatric patients after cardiothoracic surgery from the Intensive Care Units (ICUs) in Japan.Informed consent will be obtained from the their parents or legally r...

Eligibility Criteria

Inclusion

  • pediatric patients younger than two years old after cardiothoracic surgery
  • pediatric patients who have been ventilated for more than 12 hours after surgery

Exclusion

  • patients with tracheostomy
  • patients with do-not-resuscitate (DNR)
  • patients who have be treated by noninvasive positive pressure ventilation or high flow nasal cannula before surgery
  • patients who undergo unplanned extubation
  • patients who have withdrawn consent from their legal guardian
  • patients who don't need oxygen therapy
  • patients who are planned to receive treatment with noninvasive positive pressure ventilation after extubation
  • patients who are planned to inhale nitric oxide(NO) after extubation

Key Trial Info

Start Date :

August 11 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 30 2024

Estimated Enrollment :

286 Patients enrolled

Trial Details

Trial ID

NCT04451057

Start Date

August 11 2020

End Date

June 30 2024

Last Update

July 8 2024

Active Locations (1)

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Department of Anesthesiology and Intensive Care Medicine, Osaka University

Osaka, Japan