Status:
TERMINATED
Early Use of Corticosteroids in Non-critical Patients With COVID-19 Pneumonia
Lead Sponsor:
University of Chile
Conditions:
COVID-19
Eligibility:
All Genders
18-90 years
Phase:
PHASE3
Brief Summary
Steroids has shown benefits in COVID19 patients in observational studies. We hypothesized that early use of corticosteroids, low dose, in mild disease, can decrease progression to respiratory failure ...
Detailed Description
We are in the middle of a coronavirus pandemic, facing a large number of infections in serious cases and an increasing number of deaths in Chile. As of June 11, 2020, there are 154092 cases confirmed ...
Eligibility Criteria
Inclusion
- 18 years or more
- COVID-19 confirmed by PCR
- Oxygen requirements until 35 % by venturi mask or 5 lt minutes by nasal cannula
- Consent form signed
Exclusion
- Previous steroid use 48 hours or more.
- Pregnancy
- Chronic respiratory failure
- Requirements of mechanical ventilation (invasive or no invasive)
- Chronic liver damage Child Pugh B or C
- Chronic kidney disease stage IV or V.
- Immunosuppressed
- Participation on other trial.
Key Trial Info
Start Date :
June 23 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 30 2021
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04451174
Start Date
June 23 2020
End Date
January 30 2021
Last Update
June 3 2021
Active Locations (1)
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1
Hospital Santiago Oriente
Santiago, Peñalolen, Chile, 7930124