Status:
TERMINATED
Nutritional Intervention and Outcomes in Elderly After Hip Fracture Surgery
Lead Sponsor:
Peking University First Hospital
Collaborating Sponsors:
The Forth Medical Center of PLA General Hospital
Tianjin Orthopedic Hospital
Conditions:
Elderly Patients
Malnutrition
Eligibility:
All Genders
70+ years
Phase:
NA
Brief Summary
Hip fracture is one of the most frequently occurred injury in the elderly and usually requires surgical treatment. Malnutrition is common in elderly patients with hip fracture and is associated with w...
Detailed Description
Elderly patients with hip fracture have a high rate of malnutrition. In a cohort study of hip fracture patients aged 70 years or older, 18.8% have malnutrition and 44.6% are at risk of malnutrition. I...
Eligibility Criteria
Inclusion
- Age ≥70 years old;
- Hospitalized for hip fracture, scheduled to undergo hip-fracture surgery within 48 hours;
- Classified as malnutrition or at risk of malnutrition according to the short form mini-nutrition assessment (MNA-SF);
- Provide written informed consents.
Exclusion
- Pathological fracture;
- History of schizophrenia, epilepsy, Parkinson's disease, or myasthenia gravis before surgery;
- Unable to communicate due to coma, severe dementia, or language barrier;
- Unable to eat due to any disease in the gastrointestinal system;
- Severe hepatic dysfunction (Child-Pugh class C), renal failure (requirement of renal replacement therapy), respiratory failure (requirement of respiratory support), cardiac insufficiency (New York Heart Association classification ≥IV), or American Socisty of Anesthesiologists classification ≥IV;
- Preexisting organ injury before surgery (delirium, acute kidney injury, myocardial injury, etc.);
- Other conditions that are considered unsuitable for study participation.
Key Trial Info
Start Date :
December 28 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 2 2021
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04451538
Start Date
December 28 2020
End Date
April 2 2021
Last Update
August 5 2025
Active Locations (3)
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1
Peking University First Hospital
Beijing, Beijing Municipality, China, 100034
2
Fourth Medical Center of PLA General Hospital
Beijing, Beijing Municipality, China, 100048
3
Tianjin Orthopedic Hospital
Tianjin, Tianjin Municipality, China