Status:

UNKNOWN

Probe-based Confocal Laser Endomicroscopy in Critically Ill COVID-19 Patients

Lead Sponsor:

Federal Research Clinical Center of Federal Medical & Biological Agency, Russia

Conditions:

COVID-19

Eligibility:

All Genders

18-90 years

Phase:

NA

Brief Summary

The study is devoted to the comparative analysis of the data received in patients with COVID-19 lung pathology using the method of probe-based confocal laser endomicroscopy of distal airways and two r...

Eligibility Criteria

Inclusion

  • Patient Informed Consent;
  • the diagnosis of COVID-19 or one of the following lung diseases: chronic obstructive pulmonary disease, pneumonia, solitary nodule, pulmonary sarcoidosis, idiopathic interstitial pneumonia, hypersensitivity pneumonitis, pulmonary vasculitis, pulmonary eosinophilia, hemochromatosis, histiocytosis X, pulmonary lymphangioleiomyomatosis; alveolar proteinosis, other rare lung disease
  • high resolution computed tomography scans performed not later than one month before pCLE (for non-COVID-19);
  • planned or performed histology (for non-COVID-19)
  • Severe respiratory failure,

Exclusion

  • pregnancy or breast feeding,
  • lung bleeding,
  • any acute or chronic disease that may be a contraindication to bronchoscopy,
  • any diseases of hematopoietic system,
  • taking part in other clinical trials

Key Trial Info

Start Date :

August 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2021

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04451889

Start Date

August 1 2020

End Date

September 1 2021

Last Update

July 24 2020

Active Locations (1)

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Federal Research Clinical Center FMBA Russia

Moscow, Russia, 115682