Status:

COMPLETED

Physiological Response to 5 Days Fasting

Lead Sponsor:

Charite University, Berlin, Germany

Conditions:

Healthy

Eligibility:

All Genders

20-50 years

Phase:

NA

Brief Summary

To investigate energy metabolism, anthropometry, blood pressure, gut microbiome, serum metabolome, glucose variability and neural mechanisms of food choice and mood before and after 5 days of fasting ...

Eligibility Criteria

Inclusion

  • Men and women
  • 20-50 years
  • Body mass index 20-30 kg/m2

Exclusion

  • Clinically relevant heart, lung, liver, and kidney diseases
  • Any prescribed medication (except for oral contraceptives)
  • Current or chronic infection
  • Intake of antibiotics within 6 months before study entry
  • Fasting week within 6 months before study entry
  • Habitual use of dietary supplements
  • Food intolerances
  • Pregnancy, lactation
  • Vegan diet
  • Smokers
  • In addition for fMRI: sensorineural hearing loss, tinnitus, metal implants, electric devices

Key Trial Info

Start Date :

November 2 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2024

Estimated Enrollment :

55 Patients enrolled

Trial Details

Trial ID

NCT04452916

Start Date

November 2 2020

End Date

July 1 2024

Last Update

August 21 2024

Active Locations (1)

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Charité Universitätsmedizin Berlin

Berlin, Germany, 13125