Status:
TERMINATED
Development and Validation of a Model to Predict Fast Progression in Glaucoma
Lead Sponsor:
Duke University
Collaborating Sponsors:
Genentech, Inc.
Conditions:
Glaucoma
Primary Open Angle Glaucoma
Eligibility:
All Genders
40-90 years
Brief Summary
1. The purpose of this study is to obtain genetic data on a well-defined population of patients with glaucoma that had accurate measurements of rates of structural and functional change over time. 2. ...
Detailed Description
The purpose of this study is to obtain genetic data on a well-defined population of patients with glaucoma that had accurate measurements of rates of structural and functional change over time, develo...
Eligibility Criteria
Inclusion
- Phase I:
- Inclusion Criteria:
- 1\. Subjects will be identified from a previous database search (PRO00103899) with glaucoma or suspicion of glaucoma based on International Classification of Diseases (ICD) codes at baseline.
- Phase II:
- Inclusion criteria:
- Subjects must be between the ages of 40 and 90 years old;
- Both males and females will be included.
- Be able and willing to provide signed informed consent and follow study instructions
- Exclusion criteria:
- Subjects will be excluded if they present with any systemic or ocular conditions that in the opinion of the Principal Investigator may prevent them from completing the tests (e.g. history of seizures or pathologies affecting the vestibular system or lower limbs).
- Women of child-bearing potential will be excluded from tests that require pupil dilation, unless they have already received dilating drops as part of their standard of care.
Exclusion
Key Trial Info
Start Date :
July 20 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 24 2023
Estimated Enrollment :
1152 Patients enrolled
Trial Details
Trial ID
NCT04454190
Start Date
July 20 2021
End Date
April 24 2023
Last Update
March 25 2024
Active Locations (1)
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1
Duke University Eye Center
Durham, North Carolina, United States, 27705