Status:

COMPLETED

Pulsed Radiofrequency and Osteoarthritic Chronic Knee Pain

Lead Sponsor:

University of Rome Tor Vergata

Conditions:

Pulsed Radiofrequency

Osteoarthritis, Knee

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

The purpose of this study is to investigate the efficacy and safety of pulsed radiofrequency of the saphenous nerve in the treatment of pain due to knee osteoarthritis (OA). The investigators will con...

Detailed Description

Osteoarthritis (OA) affects 10% of the population over 60 years of age each year, with an increasing incidence related to population aging. This disease costs 1-2.5% of GDP on average in Europe when c...

Eligibility Criteria

Inclusion

  • Chronic knee pain (present for at least 6 months), of moderate-severe intensity (assessed by NRS =\> 6), not responsive to conservative treatments (physiotherapy, oral analgesics).
  • Diagnosis of knee osteoarthritis confirmed by instrumental investigation (X-ray and/or MRI) and Oxford Knee Score = \<35.
  • Positivity to the diagnostic block of no. saphenous (defined as a reduction of at least 50% of the NRS score).
  • If the patient is taking opioids or other morphine equivalents, the dosage should not be changed within 3 months prior to the study enrollment visit.

Exclusion

  • Body Mass index \> 40 kg /m2
  • History of systemic inflammatory disease, uncontrolled diabetes mellitus, neoplastic pathology, coagulopathy
  • Previous knee replacement implant

Key Trial Info

Start Date :

January 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2021

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT04454710

Start Date

January 1 2020

End Date

February 1 2021

Last Update

March 17 2021

Active Locations (1)

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University of Rome Tor Vergata

Rome, Lazio, Italy, 00133