Status:
UNKNOWN
Study on the Rule and Mechanism of Treating Functional Gastrointestinal Diseases From the Perspective of Liver and Spleen
Lead Sponsor:
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Conditions:
Non-erosive Reflux Disease/Diarrheal Irritable Bowel Syndrome
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
To clarify the changes of intestinal flora - gut - brain axis in FGIDs patients represented by NERD disharmony of liver and stomach and IBS-D disharmony of liver and spleen, and confirm that the imbal...
Eligibility Criteria
Inclusion
- Healthy volunteers with no abnormal clinical manifestations;
- Meet the diagnostic criteria of NERD syndrome of disharmony of liver and stomach and IBS-D syndrome of liver depression and spleen deficiency.
- Aged between 18 and 70.
- Did not take antibiotics, steroids or other hormones, Chinese herbal preparations (including oral and intravenous administration), microecological preparations or probiotics such as yogurt for nearly a week;
- Subjects are informed and sign informed consent voluntarily;
- Have certain reading ability.
Exclusion
- Patients with severe lesions of the heart, liver, kidney and other major organs, hematopoietic system, nervous system or mental diseases;
- Complicated with other organic diseases of the digestive system (such as peptic ulcer), or systemic diseases that affect the dynamics of the digestive tract (such as hyperthyroidism and diabetes);
- Ongoing or ongoing use of drugs that may affect gastrointestinal function (antidiarrals, antidepressants, anti-anxiety drugs, intestinal microflora regulation drugs, antibiotics, etc.);
- Those with a history of allergy to related drugs or severe food allergy used in the research.
- The body is colonized with metal medical devices. (6) Having a pregnancy plan within three months.
- \-
Key Trial Info
Start Date :
June 25 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 30 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04454996
Start Date
June 25 2020
End Date
March 30 2022
Last Update
July 2 2020
Active Locations (1)
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1
Xiyuan Hospital of China Academy of Chinese Medical Science
Beijing, Beijing Municipality, China, 100091