Status:
UNKNOWN
Comparison of Thawing Embryos in Advance and on the Day of Transfer on Pregnancy Outcomes in FET Cycle
Lead Sponsor:
Jinan Central Hospital
Conditions:
In Vitro Fertilization
Frozen Embryo Transfer
Eligibility:
FEMALE
25-35 years
Phase:
NA
Brief Summary
Respectively for patients with repeated transplant failure and routine patients, Thawing frozen embryos in advance (18h) to extend the duration of embryonic development or thawing embryos on the day o...
Detailed Description
Although in clinical practice, thawed embryos with appropriate development time will be selected strictly according to the number of days after ovulation, there are still two problems in actual clinic...
Eligibility Criteria
Inclusion
- Aged \<=35 years old;
- Regular menstrual cycle;
- Baseline follicle stimulating hormone (FSH) \<12 IU/L;
- Infertility, pure fallopian tube or/and male factor;
- At least 2 high-quality day 3 embryos or 1 high-quality day 5 blastocyst are used for ET.
Exclusion
- Patients with repeated transplant failure:
- Abnormal uterus, such as adenomyosis, endometriosis, endometrial polyps or Asherman syndrome;
- Abnormal ovaries, such as low ovarian response and polycystic ovary syndrome (PCOS);
- The endometrial thickness of FET day is \<7 mm.
Key Trial Info
Start Date :
January 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 30 2021
Estimated Enrollment :
500 Patients enrolled
Trial Details
Trial ID
NCT04455191
Start Date
January 1 2020
End Date
June 30 2021
Last Update
July 7 2020
Active Locations (1)
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1
Jinan Central Hospital Affiliated to Shandong University
Jinan, Shandong, China, 250013