Status:
COMPLETED
Adipokines, Inflammation, Insulin Resistance and Endothelial Dysfunction in Preeclampsia
Lead Sponsor:
Tanta University
Conditions:
Pre-Eclampsia
Eligibility:
FEMALE
25-35 years
Brief Summary
The aim of the present study is to evaluate the implication of adipokines, inflammation, insulin resistance and endothelial dysfunction in the pathogenesis of preeclampsia and in pregnancy related com...
Detailed Description
This observational parallel study will be conducted on pregnant women with normal pregnancy, pregnant women with Preeclampsia, and on healthy non-pregnant women. All participants will be recruited fro...
Eligibility Criteria
Inclusion
- Pregnant women with normal pregnancy (n=20)
- Pregnant women with Preeclampsia (n=20) at their third trimesters of pregnancy will be included in the study. Preeclampsia will be defined and diagnosed by constant elevation in blood pressure greater than 140/90 mmHg and by the presence of proteinuria above 300 mg /24 hour with the absence of both urinary tract infection and previous history of hypertension.
- Apparently healthy non-pregnant females (n=20) will be included in this study also.
Exclusion
- Women with risk factors for oxidative stress such as smokers and
- Those with a medical history of diabetes mellitus (DM) and Tuberculosis (T.B).
- Women with a history of hypertension, familial hyperlipidemia, liver diseases, inflammatory diseases, and renal impairment.
- Non-pregnant women on hormonal therapy or hormonal contraceptives.
Key Trial Info
Start Date :
April 25 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2019
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04455204
Start Date
April 25 2016
End Date
October 1 2019
Last Update
July 7 2020
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.