Status:

RECRUITING

Language and Brain Rhythms

Lead Sponsor:

Hospices Civils de Lyon

Conditions:

Healthy Volunteers

Eligibility:

All Genders

18-40 years

Phase:

NA

Brief Summary

For humans and other animals, predicting the timing of sensory events is essential for their daily behavior. Importantly, natural sensory stimulation (such as movements, music, or speech) can present ...

Eligibility Criteria

Inclusion

  • For all experiments:
  • 18- 40 years old
  • Registration with the French healthcare system
  • Informed consent
  • Normal hearing
  • Additionally, for experiments 2,3 and 4 :
  • \- Right handed
  • Additionally, for experiment 3 and 4:
  • \- French as native language

Exclusion

  • For All Experiments:
  • Neurological or psychiatric illnesses or a history of such problems that could impact quality/variability of data or cooperation and retention of the subject in the study
  • Regular use of medications that impact the central nervous system
  • Regular use of medications, such as opioids and antidepressants, including SSRIs and tricyclic antidepressants
  • Severe hearing loss
  • A history of stroke or recent trauma to the head
  • Persons unable to adhere to abstinence from the use of drugs or alcohol the day or evening before experimental sessions
  • Women who are pregnant, breastfeeding, or have given birth in the last 6 months
  • Additionally, for experiment 2,3 and 4 :
  • A pacemaker, insulin or other pump, neurostimulator, cochlear implants or other hearing aid, metal stents, prosthesis, or implants, intracerebral clips, implantable defibrillator, cerebral shunt or ventricular catheter, other foreign metal objects in the upper part of the body
  • any dental apparatus containing metal including or root canals
  • any foreign metallic object anywhere in the body
  • bolts, screws
  • orthopedic devices or implants
  • Additionally, for experiment 3 and 4:
  • claustrophobia
  • glasses (given the participant cannot use contact lenses)
  • a head size incompatible with the use of a personalized 3D headcast or a magnetoencephalography
  • Persons having had any surgery prior to the study which puts them at risk for metal objects left in the body

Key Trial Info

Start Date :

February 18 2021

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

October 18 2026

Estimated Enrollment :

356 Patients enrolled

Trial Details

Trial ID

NCT04457622

Start Date

February 18 2021

End Date

October 18 2026

Last Update

April 9 2025

Active Locations (1)

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1

Centre de Recherche en Neuroscience de Lyon

Bron, France, 69500