Status:

RECRUITING

Restoration of Thumb Strength and Function in Basal Joint Arthritis: A Comparative Effectiveness Trial (RESTART)

Lead Sponsor:

Dartmouth-Hitchcock Medical Center

Conditions:

Osteoarthritis Thumb

Eligibility:

All Genders

21+ years

Brief Summary

The purpose of this study is to evaluate the basis for three widely held fundamental tenets about surgical intervention for thumb basal joint arthritis; 1. Trapeziectomy with ligament reconstruction ...

Detailed Description

Study Procedures: Upon obtaining informed consent and within 4 weeks of the planned date of surgery, each site coordinator will collect baseline clinical and demographic information, a visual analogue...

Eligibility Criteria

Inclusion

  • Males and females 21 years of age or older;
  • Undergoing elective non-prosthetic, primary basal joint arthroplasty;
  • Patient has necessary mental capacity to participate and comply with study protocol;
  • Patient is willing and able to give informed consent; and
  • Patient is willing to participate under the care of their chosen surgeon.

Exclusion

  • Patients with a diagnosis of rheumatoid arthritis, systemic lupus erythematosis, psoriatic arthritis, or other related inflammatory arthritis;
  • Patients undergoing simultaneous bilateral hand procedures of any nature;
  • Women who are pregnant or breastfeeding;
  • Women of reproductive potential unless there is a negative urine pregnancy test on the day of surgery. Women of child bearing potential include those who are premenopausal who have not had a bilateral oophorectomy, hysterectomy or tubal ligation. Post-menopausal is defined as not having had a menstrual period for at least one calendar year.
  • Vulnerable patient populations including prisoners and institutionalized individuals.

Key Trial Info

Start Date :

June 29 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2026

Estimated Enrollment :

165 Patients enrolled

Trial Details

Trial ID

NCT04458584

Start Date

June 29 2020

End Date

December 31 2026

Last Update

April 13 2025

Active Locations (1)

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Dartmouth-Hitchcock Medical Center

Lebanon, New Hampshire, United States, 03756