Status:
COMPLETED
HIV, Immune Activation and Salt Sensitive Hypertension
Lead Sponsor:
Mulungushi University
Collaborating Sponsors:
University of Zambia
Vanderbilt University Medical Center
Conditions:
HIV-1-infection
Hypertension,Essential
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
High dietary salt is associated with immune activation, elevated levels of inflammatory cytokines and hypertension in murine models. Hypertension is independently associated with inflammation in both ...
Eligibility Criteria
Inclusion
- Adults (aged 18 and above) who will be required to verbally consent and sign a consent form
- HIV positive or HIV Normotensive individuals or hypertensive If HIV, on antiretroviral therapy ART treated hypertensive individuals
Exclusion
- Existence of comorbidities such as diabetes mellitus and cancer Existing and recent past opportunistic infections, syphilis, hepatitis C and B virus infection and tuberculosis infection;
- Sick persons (clients seeking healthcare due to an illness rather than routine ART clinic reviews)
- Those with recent and current alcohol consumption and smoking status
Key Trial Info
Start Date :
January 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2019
Estimated Enrollment :
85 Patients enrolled
Trial Details
Trial ID
NCT04459741
Start Date
January 2 2019
End Date
December 31 2019
Last Update
July 7 2020
Active Locations (1)
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1
Livingstone Central Hospital
Livingstone, Southern Province, Zambia, 10101